cancer

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What is the function of tumor suppressor genes?

The function of tumor suppressor genes includes the following:

• Detect and repair damage or copying errors in the DNA during replication.
• If DNA damage cannot be repaired, stop further cell growth and division, and initiate apoptosis.
• Stop the cells from proliferating by a process known as contact inhibition. Contact inhibition […]
  

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What are the targeted therapies for invasion and metastasis?

There are several proteins and cellular signals that tumor cells employ for promoting invasion and metastasis. Many therapies targeting invasion and metastasis are in development.

TGF-B inhibitors

Transforming growth factor beta (TGF-B) is a protein (cytokine) secreted by all types of white blood cells. TGF-B family has many […]

What therapies target limitless replication in cancer?

Targeted therapies for halting limitless replication in cancer revolves around interfering with the cell cycle progression in cancer cells. Several small molecule drugs targeting the cancer cell’s limitless replication have entered the clinical trial stage:

Anti Telomerase agents

Each time a cell divides, it loses a fragment […]

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