cancer

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What is Unituxin (dinutuximab), and how does it work?

Unituxin (dinutuximab) is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior firstline multiagent, multimodality therapy.

What […]

What are the side effects of Kadcyla?

Hepatotoxicity

Left Ventricular Dysfunction

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in […]

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Inhibitors of CYP3A4 Clinical Impact: The concomitant use of Subsys and CYP3A4 inhibitors can increase the plasma concentration of fentanyl, resulting in increased or prolonged opioid effects, particularly when an inhibitor is added after a stable dose of Subsys is achieved. After stopping a CYP3A4 inhibitor, as the effects of the inhibitor […]